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Gender and age difference in risk factor distribution, trend, and long-term outcome of patients undergoing isolated coronary artery bypass graft surgery

BMC Cardiovascular Disorders Sep 29, 2021

Sattartabar B, Ajam A, Pashang M, et al. - Dyslipidemia (DLP) was revealed as the most frequent coronary artery disease risk factor (CADRF) in the CABG population but declining levels of low-density lipoprotein (LDL) and triglyceride (TG) were evident. Higher major adverse cardiovascular events (MACE) occurred after CABG in females.

  • This registry-based serial cross-sectional study included 24,328 patients who had isolated CABG.

  • CADRFs distribution and trend over 10 years as well as the long-term result of CABG in different age-gender categories were evaluated.

  • In all patients, the following were identified as the most frequent risk factors: DLP (56.00%), hypertension (HTN) (53.10%), diabetes mellitus (DM) (38.40%), and positive family history (38.30%).

  • Women exhibited higher prevalence of HTN, DLP, DM, obesity, and positive family history, all statistically significant.

  • Following inverse probability weighting, lower MACEs occurred in men during follow-up (HR 0.72) and no significant difference in survival was observed between genders.

  • In both genders, higher mortality and MACEs were observed in relation to DM and HTN.

  • Female population CADRFs as well as their prevention merit greater attention of health care providers and legislators.

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