Gender and age difference in risk factor distribution, trend, and long-term outcome of patients undergoing isolated coronary artery bypass graft surgery
BMC Cardiovascular Disorders Sep 29, 2021
Sattartabar B, Ajam A, Pashang M, et al. - Dyslipidemia (DLP) was revealed as the most frequent coronary artery disease risk factor (CADRF) in the CABG population but declining levels of low-density lipoprotein (LDL) and triglyceride (TG) were evident. Higher major adverse cardiovascular events (MACE) occurred after CABG in females.
This registry-based serial cross-sectional study included 24,328 patients who had isolated CABG.
CADRFs distribution and trend over 10 years as well as the long-term result of CABG in different age-gender categories were evaluated.
In all patients, the following were identified as the most frequent risk factors: DLP (56.00%), hypertension (HTN) (53.10%), diabetes mellitus (DM) (38.40%), and positive family history (38.30%).
Women exhibited higher prevalence of HTN, DLP, DM, obesity, and positive family history, all statistically significant.
Following inverse probability weighting, lower MACEs occurred in men during follow-up (HR 0.72) and no significant difference in survival was observed between genders.
In both genders, higher mortality and MACEs were observed in relation to DM and HTN.
Female population CADRFs as well as their prevention merit greater attention of health care providers and legislators.
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