Zivkovic M, et al. - A prospective, cross- sectional study is done to compare ganglion cell (GCL) and inner plexiform layer (IPL) thickness in patients at different stages of primary open-angle glaucoma (POAG), ascertain their sensitivity and specificity values, and correlate thickness values with mean deviations (MD). The outcome suggests GCL + IPL layer thickness is a highly specific and sensitive parameter in differentiating glaucomatous from healthy eyes displaying progressive damage as glaucoma worsens. Loss of this layer is highly correlated with overall loss of visual field sensitivity.