Tran J, et al. - Quantitative and clinical gait assessments were conducted in 330 non-disabled community-dwelling adults aged ≥65 years by the researchers in order to ascertain whether the gait abnormalities had any contribution to the risk of falls and disability in old patients with chronic kidney disease (CKD). Out of 330 participants, 134 individuals had CKD. Shorter stride length and greater time in the stance and double-support phases were the gait cycle abnormalities observed in CKD patients along with slower gait speed. An independent association of lower estimated glomerular filtration rate (eGFR) with the severity of gait cycle abnormalities was recognized in CKD individuals. Furthermore, the association of lower eGFR with slower gait speed was mediated via these abnormalities. However, most participants with CKD had no recognizable gait phenotype, short steps and marked swaying or loss of balance was more common in such patients on clinical gait examination, constant with the quantitative abnormalities. A greater risk of falls among participants with CKD was correlated to a gait phenotype determined by any such abnormal signs. Hence, CKD in older adults was observed as related to quantitative gait abnormalities, which clinically manifested in a gait phenotype that was associated with risk of fall.