Jacobsson L, et al. - Researchers used internationally established traumatic brain injury (TBI) outcome measures to evaluate persons on average 16 years after their injury and ascertain changes over 6 years in the overall outcome, living condition, marital status, and vocational situation, as well as in their functioning and disability. For this investigation, 49 people (mean age 45 years, 28-70 years) who were evaluated 6-15 years (average 10 years) post-TBI were reassessed 12-21 years following their injury (average 16 years). The overall result using the Glasgow Outcome Scale (GOS) was unchanged for a large majority from the first to the second assessment and no significant changes in marital status or vocational condition were noticed. There was a decline in cognitive function, home integration, and social integration, which was significant, but very small. The very small changes over 6 years imply that people with a TBI can achieve and maintain a stable level of long-term post-TBI functioning. Women with moderate to severe TBI appear to be more vulnerable and may experience a small decline related to anxiety, depression, irritability, pain, and headache, as well as fatigue in some aspects of their functioning. To validate these results, the relatively small sample needs further research.