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Fumarate hydratase (FH) deficiency in uterine leiomyomas: Recognition by histological features vs blind immunoscreening

Virchows Archiv Jan 27, 2018

Siegler L, et al. - Authors here aim at reporting the frequency and morphology of FH-deficient uterine leiomyomas. As per findings, FH-deficient uterine leiomyomas are rare in routine material. Consistent morphological features could reliably identify them. For detecting them, predictive morphology seems superior to blind immunohistochemistry (IHC) screening.
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