Yanagisawa R, et al. - Given cognitive impairment might affect procedure outcomes in patients undergoing transcatheter aortic valve implantation (TAVI), researchers assessed the prevalence of preprocedural cognitive impairment, as well as its influence post-TAVI using data for patients aged ≥70 years from the Optimized CathEter vAlvular iNtervention (OCEAN-TAVI) registry. Cognitive impairment was seen in 420 (38%) of 1,111 patients. Cognitive impairment, based on the Mini-Mental State Examination (MMSE) score, independently predicted mortality 1 year post-TAVI. Compared with patients with normal cognition, more in-hospital adverse outcomes, including prolonged hospital stays, major bleeding, vascular complications, and acute kidney injury, but similar 30-day mortality, was reported for patients with cognitive impairment.