Chan V, Wilson JRF, Ravinsky R, et al. - A systematic review was performed to explore the relationship between frailty and outcomes after spine surgery. Researchers carried out to search electronic databases from 1946 to 2020 to distinguish articles on frailty and spine surgery. They selected 32 studies for review, with a total of 127,813 patients. The primary endpoint included adverse events. Other measures of morbidity, mortality, and patient outcomes were considered as secondary endpoints. There is strong evidence that frailty is associated with an increased risk of morbidity and mortality in patients who received spine surgery. Nevertheless, it remains inconclusive if frailty affects patient outcomes and quality of life after surgery.