Oliver WM, Searle HKC, Ng ZH, et al. - In this study, the current incidence and epidemiology of humeral diaphyseal fractures were ascertained. Researchers further evaluated change in patient and injury characteristics by fracture location within the humeral diaphysis. Researchers retrospectively distinguished all adult patients (aged ≥ 16 years) sustaining an acute fracture of the humeral diaphysis managed at the study centre from a trauma database for over ten years (2008 to 2017). They recorded and examined patient age, gender, medical/social background, injury mechanism, fracture classification, and associated injuries. They distinguished a sum of 900 fractures (typical 88.9%, n = 800/900; pathological 8.3%, n = 75/900; periprosthetic 2.8%, n = 25/900) in 898 patients (mean age 57 years (16 to 97), 55.5% (n = 498/898) female). This research demonstrates the incidence and epidemiology of humeral diaphyseal fractures. They found important variations in patient and injury characteristics based upon fracture location. According to the findings, injuries involving the proximal- and middle-thirds of the humeral diaphysis should be considered as fragility fractures.