Yang W, Zhao J, Sun L, et al. - In this retrospective, consecutive study, researchers assessed the changes in corneal endothelium cell density (ECD) and the correlated factors after Implantable Collamer Lens (ICL) V4c implantation. Twenty-five patients (48 eyes) with myopia who underwent ICL V4c implantation were selected. All surgeries were performed safely, and there were no complications during the follow-up period (average 52 ± 2.9 months). For myopia correction, ICL V4c implantation is both safe and effective. Anterior segment biometric parameters such as the vault, ACA, and C-ICL may influence ECD changes; specifically, the vault plays a significant role.