Four nights of sleep restriction suppress the postprandial lipemic response and decrease satiety
Journal of Lipid Research Sep 12, 2019
Ness KM, Strayer SM, Nahmod NG, et al. - Researchers investigated how postprandial lipemia following a standardized high-fat dinner (HFD) is affected by 5 hours’ time in bed (TIB) per night for 4 consecutive nights. They also determined if a single night of recovery sleep (10 hours TIB) is enough to restore postprandial metabolism to baseline. In all, they found a reduction of non-esterified fatty acid (NEFA) throughout the HFD because of sleep restriction, and NEFA continued to be suppressed in the recovery condition. Also, a reduction in participant-reported fullness, or satiety, as well as decreased postprandial interleukin-6 were observed as a result of sleep restriction. In this study, the impairment of postprandial lipemia was observed as a consequence of 4 nights of 5 hours’ TIB/night. Also, the possible adequacy of 1 night of recovery sleep for recovery of triglyceride metabolism, but not for markers of adipocyte function, was shown.
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