Weber J, et al. - Whether improved lung aeration and respiratory mechanics can be seen in obese patients during flow-controlled ventilation (FCV), was investigated in this study. In a randomized crossover setting, a comparison between FCV and volume-controlled (VCV) ventilation was performed among 23 obese patients. Except for the ventilation mode associated variations (VCV: inspiration to expiration ratio 1:2 with passive expiration, FCV: inspiration to expiration ratio 1:1 with active, linearized expiration), ventilation settings were kept the same, beginning with baseline measurements. The change of end-expiratory lung volume vs baseline ventilation was the primary endpoint. According to the findings, improved regional ventilation distribution of the lung at comparable positive end-expiratory-pressure, tidal volume, plateau pressure and ventilation frequency was afforded by FCV vs VCV. The reason behind the increase in end-expiratory lung volume during FCV was perhaps the raised mean tracheal pressure which can be due to the linearized expiratory pressure decline.