Morioka M, et al. - In patients with diabetic macular edema (DME), authors assessed the anterior flare intensity (AFI) and central retinal thickness (CRT) values following intravitreal injection of aflibercept (IVA), ranibizumab (IVR), or triamcinolone acetonide (IVTA). They used laser flare meter and spectral domain optical coherence tomography to measure the AFI and CRT, respectively, at days 0, 1, 7, 30, and 90. Treatment by IVTA, IVR, or IVA improved DME, whereas only the eyes treated with IVTA demonstrated the reduction in AFI. Findings suggested the likely association of the temporal profiles of AFI with the differences in the pharmacological properties of the drugs.