Marvisi M, Ferrozzi F, Balzarini L, et al. - At the end of February, the pandemic spread of the new COVID-19 involved the Lombardy region (Northern Italy). Researchers sought to report on the clinical and radiological characteristics of 90 confirmed cases with COVID-19 pneumonitis. Further, they examined their role in predicting the evolution to fibrosis. An HRCT study was conducted on all individuals on the day of admission and 8 weeks later. Treatment was provided with lopinavir + ritonavir (Kaletra) 400/100 mg 2 times a day or darunavir + ritonavir 2 times a day, and Hydroxychloroquine 200 mg 2 times a day. Pulmonary fibrosis developed in 23 patients (25.5%); male gender, smoking habit, and comorbidities were identified as risk factors. In the series of cases, “reversed halo sign” was frequent (63%) and appears to be a typical pattern of COVID-19 pneumonitis. Per findings, reversed halo sign linked with ground glass pattern may be a typical HRCT pattern of COVID-19 pneumonitis. In older males and in patients with comorbidities and bone marrow involvement, frequent evolution to pulmonary fibrosis was noted.