Wasilewicz R, et al. - Researchers performed this prospective, open-label, single-center, non-randomized study including glaucoma and healthy individuals to determine the feasibility of a novel contact lens device for intraocular pressure (IOP) and ocular pulse amplitude (OPA) continuous measurements over 24 hours. Using the pressure-measuring contact lens (PMCL) device they acquired IOP and OPA values in one patient’s eye at the beginning of the measurement and compared the values with tonometry values (Goldman applanation tonometry (GAT) and dynamic contour tonometry (DCT)) in the same eye just before PMCL placement. They obtained 24 hr IOP and OPA curves for eight individuals. In 75% (GAT) and 87.5% (DCT) of individuals, PMCL and tonometry had the mean IOP difference within ±5 mm Hg in the same eye. PMCL and DCT allowed detection of variations in IOP due to water drinking test; they showed an average increase of 2.43 and 1.85 mm Hg, respectively. In fellow eyes, differences between PMCL and DCT were within ±5 mm Hg for IOP variations for 97.2% of time points. For 85.5% of the time points, the difference between OPA in fellow eyes was within ±5 mm Hg. They identified this work as the first to provide a proof-of-concept for 24-hour continuous measurements of IOP and OPA with the PMCL. This device affords a non-invasive tool and displayed good comparability with standard tonometry.