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Fifty years’ follow-up of childhood epilepsy: Medical outcome, morbidity, and medication

Epilepsia Jan 24, 2019

Brorson LO, et al. - Using medical records and a questionnaire, researchers conducted a prospective longitudinal study to characterize the long-term prognosis of childhood epilepsy, with particular emphasis on seizure remission, relapse, medication, associated neurologic impairment, mortality rate, and cause of death. The study sample consisted of 195 children with epileptic seizures in 1962-1964. This 50-year, long-term follow-up of a cohort of people with childhood epilepsy shows a better outcome for seizure freedom than follow-up after 12 years and previous reports. In addition, a low incidence of seizure relapses was reported. Remission of seizures did not automatically lead to medication termination. The SUDEP (sudden unexpected death in epilepsy) mortality rate was lower than previously reported.

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