Ceccanti S, Cervellone A, Pesce MV, et al. - Via this 6-year, single center, non-randomized interventional study (2013-2019), researchers sought to compare surgical outcomes of open inguinal hernia repair (IHR) performed under spinal anesthesia (SA) vs general anesthesia (GA) in neonates and infants. In addition, they identified criteria to prognosticate the success or failure of SA. SA and GA were used in 68 infants (78 IHR) and 37 infants (44 IHR) at the discretion of the anesthesiologist, respectively. Outcomes of this pilot study confirm the safety and effectiveness of SA with no detrimental effect on surgical outcome of neonates and infants undergoing IHR. In addition, it may aid in further defining the patients that may have a successful SA. Per researchers experience, SA is particularly suitable in infants weighing < 4000 g, and conversion to GA associates with prolonged operative time.