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Family-based intervention in adolescent restrictive eating disorders: Early treatment response and low weight suppression is associated with favourable one-year outcome

BMC Psychiatry Sep 20, 2017

Swenne I, et al. - This study was performed to examine the one-year outcome of a family-based intervention programme with defined and decisive interventions at the start of treatment. The observations that low weight and high eating disorders (ED) cognitions gave a poor prognosis but that rapid weight gain at the start of treatment predicted a better prognosis was presently extended to adolescents with restrictive ED with a wide range of body mass index (BMI) at presentation. At follow-up, high weight suppression was correlated with a poor prognosis and indicated the importance of taking premorbid BMI into account when setting weight targets for treatment.

Methods
  • The authors examined data concerning 201 adolescents with restrictive ED with features of anorexia nervosa but not fulfilling the weight criterion starting treatment 2010-2015.
  • Subjects had a wide range of body mass index (BMI) and of weight loss at presentation, and completed a one-year follow-up.
  • They defined recovery from the ED as an Eating Disorder Examination-questionnaire (EDE-Q) score < 2.0 or as not fulfilling criteria for an ED at a clinical interview.

Results
  • At 1 year, by EDE-Q 130 (65%) had recovered and by clinical interview 106 (53%).
  • According to the EDE-Q criterion recovery was independently associated with the lower EDE-Q score at presentation, higher weight gain after 3 months of treatment and lower weight suppression at follow-up, weight suppression being defined as the difference between premorbid and current BMI.
  • For an ED, not fulfilling criteria was correlated with the same factors and also by higher BMI at presentation.
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