Pedersen CJ, et al. - Researchers examined a prospective cohort of consecutive emergency departments (EDs) patients with acute respiratory illness (ARI) for the issues related with influenza in ED setting. Between December 2016 and March 2017, consecutive ED patients with ARI symptoms were screened by trained research assistants. Criteria for ARI were measured fever at home or in the ED >38°C and a cough, sore throat, or rhinorrhea with a duration of symptoms >12 hours and <1 week. They enrolled 119 patients, 31% of whom were positive for influenza. Distinguishing factors for influenza cases included the presence of myalgia, the absence of gastrointestinal symptoms, and oxygen saturation ≥97%; these may help to distinguish these cases from other acute respiratory illness cases in the ambulatory ED population.