Kulalert P, Phinyo P, Patumanond J, et al. - Among children with severe asthma exacerbation (SAE), researchers conducted this retrospective cohort study to examine factors correlated with a poor response to intermittent nebulized short-acting beta-agonists (SABA). The sample consisted of children diagnosed with SAE according to the definition of the British Guidelines on the Management of Asthma, who were admitted at Hat Yai Hospital from January 1, 2015, to December 31, 2017. All children have been treated with intermittent SABA nebulization. Participants in the study were 133 children (59 were in the failure group and 74 were in the success group). Four prognostic factors for treatment failure in children with SAE have been identified: a previous history of intubation; receiving < 3 doses of nebulized salbutamol in the emergency room (ER), oxygen saturation at ER < 92%; and exacerbation triggered by pneumonia.