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Factors associated with delayed transition to oral feeding in infants with single ventricle physiology

The Journal of Pediatrics Apr 05, 2019

Kurtz JD, et al. - In this single center, retrospective study, researchers characterized the duration of time to achieve exclusive oral feeding in infants with single ventricle physiology and identified risk factors correlated with prolonged gastrostomy tube dependence. Duration of time required to achieve oral feeding was the primary outcome. By Glenn palliation (early), by 1 year of age (mid), or after 1 year of age (late), they defined transition periods as exclusive oral feeding. Investigators found that the group that achieved early transition had a higher percentage of preoperative oral feeding, greater weight-for-age z score at initial discharge, shorter initial intensive care unit duration, shorter initial hospital length of stay, and greater weight-for-age z score at Glenn admission. No preoperative oral feeding and more cardiac medicines were related to failure to achieve an early transition at initial discharge. No preoperative oral feeding and longer duration of the initial intensive care unit duration were linked to failure to achieve mid-transition. Overall, they suggested that preoperative oral feeding could be a modifiable factor for improving the early transition to oral feeding.
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