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Factors associated with antihypertensive monotherapy among US adults with treated hypertension and uncontrolled blood pressure overall and by race/ethnicity, NHANES 2013-2018

American Heart Journal Oct 21, 2021

Zheutlin AR, Derington CG, King JB, et al. - The probability of combination antihypertensive therapy was higher in relation to clinical and healthcare-access factors, including a healthcare visit within the previous year and co-morbid conditions.

  • This cross-sectional analysis of National Health and Nutrition Examination Surveys (NHANES; 2013–2014 through 2017–2018) involved 1,597 participants (age ≥20 years) with hypertension and uncontrolled blood pressure (BP).

  • Monotherapy prevalence, adjusted by age and gender, was 42.6% overall, 45.4% in non-Hispanic White, 31.9% in non-Hispanic Black, 39.6% in Hispanic, and 50.9% in non-Hispanic Asian adults.

  • Overall, higher monotherapy use was reported in relation to higher systolic BP, while lower monotherapy use was observed in relation to older age, having a healthcare visit in the previous year, higher BMI, and having heart failure.

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