Terman SW, et al. - In order to define the cumulative incidence of readmissions following a seizure-associated hospitalization, as well as to define risk factors and readmission diagnoses, researchers undertook a retrospective cohort study involving adults hospitalized with a primary discharge diagnosis of seizure. They used the State Inpatient Databases across 11 states from 2009 to 2012. Findings revealed a common incidence of readmission following hospitalization for seizures. Readmission within 30 days was sought by 13,929 (14%) of 98,712 patients. Epilepsy/convulsions, mood disorders, schizophrenia, and septicemia were reported as the causes of readmission. Diagnoses of CNS tumor or psychosis, urgent index admission, transfer to nonacute facilities, long length of stay, and for-profit hospitals were identified as the strongest predictors of readmission. The c-statistic of the main model was 0.66. Index admission for status epilepticus, low hospital epilepsy volume, and rural hospitals were documented as predictors of readmission for status epilepticus. Recurrent seizures, the most common readmission diagnosis, should thus be the primary target of prevention strategies, noted the investigators. Although many factors related to readmission were revealed, readmissions continue to be challenging to predict.