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Exposure to contrast media in the perioperative period confers no additional risk of acute kidney injury in surgical patients

Nephrology Dialysis Transplantation Oct 06, 2018

Zealley I, et al. - Researchers investigated if the risk of post-operative acute kidney injury (AKI) is influenced by the timing of contrast media (CM) exposure connected to diagnostic imaging during the immediate perioperative period. Participants were patients aged 18 years or older who had diagnostic imaging within 7 days of non-cardiac surgery between January 1, 2003 and December 31, 2013 in the Tayside region of Scotland, UK. Based on the findings, they concluded that avoiding the administration of CM, which limits the quality of the computed tomography (CT) scan, is not required for patients who have either just had or are soon to undergo general surgical procedures. Contrast-enhanced CT scans may benefit these patients, in terms of diagnostic value, without increasing the risk of perioperative AKI. Increasing age, male gender, lower baseline renal function and treatment with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers were identified as independent predictors of post-operative AKI on multiple logistic regression.

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