Exposure to bisphenols and asthma morbidity among low-income urban children with asthma
The Journal of Allergy and Clinical Immunology Jul 31, 2020
Quirós-Alcalá L, Hansel NN, McCormack M, et al. - As it remains unclear whether exposure to bisphenol A (BPA) or its structural analogs bisphenol S (BPS) and bisphenol F (BPF) is correlated with asthma morbidity, researchers conducted this investigation to explore the connections between bisphenols and pediatric asthma morbidity. Concentrations of BPA, BPS, and BPF were quantified in 660 urine samples from 148 predominantly low-income, African American children, 5-17 years of age, with established asthma. Generalized estimating equations were used to examine connections between concentrations or detection of urinary bisphenols and morbidity outcomes and assessed heterogeneity of associations by gender. Evidence has been found that BPA exposure in a predominantly low-income, minority pediatric cohort is correlated with asthma morbidity and that associations may vary by gender. Given the high pediatric asthma burden and widespread exposure to BPA in the United States, the results support further research.
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