Lara-Cinisomo S, et al. - Researchers explored the relationship of perinatal depression with lower oxytocin (OT) levels among Latinas who are at high risk of perinatal depression. Participants were 108 Latinas in the third trimester of pregnancy. They assessed depression and urinary OT levels during pregnancy and 6 weeks postpartum. Outcomes revealed persistently higher mean OT levels over time among participants who were depressed or anxious at 6 weeks postpartum. These findings suggest the possible significance of OT levels as a neuroendocrine factor that contributes to depressive and anxious symptoms. In the whole sample, OT levels declined significantly from prenatal to postpartum, though a significant change in OT levels with was not seen in participants with probable prenatal depression.