Gracitelli CPB, de Faria NVL, Almeida I, et al. - Researchers conducted this prospective observational study to assess exercise-induced changes in ocular blood flow (OBF) parameters in patients with primary open-angle glaucoma (POAG). Furthermore, possible factors associated with OBF parameter changes immediately after exercise were examined. Intraocular pressure (IOP; Goldman applanation tonometry), mean arterial pressure (MAP), ocular pulse amplitude (OPA; assessed by dynamic contour tonometry), and ocular perfusion pressure (OPP; 2/3 MAP – IOP) were measured and compared immediately before and 1 and 30 min after the exercise. In total, 30 eyes (30 patients; mean age was 62.9 ± 1.7 years) were involved. According to findings, aerobic exercise in POAG patients results in a significant short-term increase in OBF parameters. Although IOP appears to be a modest elevation, it is accompanied by a significant increase in MAP, which results in higher OBF measurements. Short-term modifications induced by exercise and its possible implications for the prognosis of glaucoma deserve further inquiry. No significant associations for OPP have been found.