Sundström B, et al. - In patients with ankylosing spondylitis (AS), researchers ascertained if modifiable risk factors (exercise or smoking habits) and disease activity measurements can be used to predict spinal immobility. For this investigation, annual clinical measurements of spinal mobility in 54 patients with AS were co-analyzed with data concerning lifestyle factors and laboratory measurements from a previous cross-sectional study. They found exercise habits, duration of disease and high-sensitivity C-reactive protein (hsCRP) to be related to the development of spinal immobility. Outcomes highlighted that exercise, as a modifiable risk factor, should continue to be an important part of non-pharmacological treatment and self-care for patients with AS, with a variety of possible positive effects, including preserved spinal mobility.