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Evolution of the oropharynx cancer epidemic in the United States: Moderation of increasing incidence in younger individuals and shift in the burden to older individuals

Journal of Clinical Oncology May 02, 2019

Tota JE, et al. - Researchers used log-linear Joinpoint regression and age-period-cohort models to evaluate the trends in oropharynx cancer incidence in recent birth cohorts in the United States from 1992 to 2015, and to assess projections through 2029, focusing on the burden across age, sex, and race/ethnicity subgroups. For this purpose, they used US cancer registry data. In young white US men, ebbing of the exponential increase in oropharynx cancer incidence was reported. In cohorts born after 1955, they found that modest increases are occurring/anticipated. A substantial shift in burden to elderly white men was predicted by continued strong increases in incidence in cohorts born prior to 1955, as well as nearly 50% increase in size of the US population aged ≥ 65 years through 2029.

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