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Evolution of the oropharynx cancer epidemic in the United States: Moderation of increasing incidence in younger individuals and shift in the burden to older individuals

Journal of Clinical Oncology Jun 22, 2019

Tota JE, et al. - Researchers focused on the changes in the trajectory of the oropharynx cancer epidemic in the United States, by analyzing data from a US cancer registry. They assessed incidence trends from 1992 to 2015 and projections through 2029 by using log-linear Joinpoint regression and age-period-cohort models. Findings highlighted a lessening of the exponential rise in oropharynx cancer incidence in young white US men, with occurrence/anticipation of modest increases in cohorts born after 1955. A substantial change in burden toward elderly white men is signified by sustained strong rises in incidence in cohorts born prior to 1955, and a nearly 50% rise in the size of the US population age 65 years or older through 2029.

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