Oh KJ, et al. - Researchers sought to describe the outcome of antibiotic treatment in 22 women meeting the following criteria: (1) singleton pregnancy; (2) painless cervical dilatation of >1 cm between 16.0 and 27.9 weeks of gestation; (3) intact membranes and absence of uterine contractions; (4) transabdominal amniocentesis performed for the evaluation of the microbiologic and inflammatory status of the amniotic cavity; (5) presence of intra-amniotic infection/inflammation; and (6) antibiotic treatment (regimen consisted of ceftriaxone, clarithromycin, and metronidazole). Outcomes revealed the resolution of the intra-amniotic inflammatory process or intra-amniotic infection in 75% of patients and treatment success in about 60% of cases among patients with cervical insufficiency and intra-amniotic infection/inflammation on receiving antibiotics (ceftriaxone, clarithromycin, and metronidazole).