Wang D, Du LY, Sun JW, et al. - In the present study, the researchers sought to examine the efficiency of Thyroid Imaging Reporting and Data System (TI-RADS) proposed by KWAK, the American College of Radiology, and the 2015 American Thyroid Association (ATA) guidelines for thyroid nodules with Hashimoto’s thyroiditis (HT) and to ascertain if HT influence the diagnostic performance of these risk-stratification systems. A total of 101 HT nodules and 101 non-HT nodules were retrospectively analyzed by ultrasound-based diagnostic classifications and contrasted with histopathological outcomes. According to findings, ACR TI-RADS performed the most effective for thyroid nodules in HT, on the other hand, KWAK TI-RADS was the best for those in non-HT. Both TI-RADS (ACR and KWAK) provided higher diagnostic efficacy than the ATA guidelines for HT or non-HT. In addition, HT may have no effect on the diagnostic efficiency of these risk-stratification systems.