Seay EG, Keenan BT, Schwartz AR, et al. - Researchers conducted this prospective cohort study to analyze the use of therapeutic nasal positive airway pressure (PAP) levels at the soft palate in anticipating the outcomes of hypoglossal nerve stimulation (HGNS) for patients with obstructive sleep apnea. Twenty-seven consecutive patients, mean (SD) age was 62.0 (14.4) years and mean BMI was 28.1 (4.0), with obstructive sleep apnea who had drug-induced sleep endoscopy (DISE) before implantation of an HGNS device have been evaluated. According to findings, therapeutic nasal PAP levels during DISE varied significantly between responder and nonresponders to HGNS. Due to the fact that DISE is a mandatory, relatively standardized diagnostic tool for HGNS candidacy, the use of therapeutic nasal PAP via DISE can be broadly implemented and studied across multiple centers to possibly improve patient selection for HGNS.