Kartasasmita A, et al. - In patients with diabetic retinopathy combined with diabetic macular edema, researchers assessed the difference in intravitreal bevacizumab (IVB) injection timing as adjuvant therapy to panretinal photocoagulation. For this retrospective nonrandomized study, they divided 40 eyes with severe non-proliferative diabetic retinopathy (NPDR) or proliferative diabetic retinopathy (PDR) into two groups; the IVB injection prior to, or after, panretinal photocoagulation. No significant difference was found in the change in central macular thickness between two groups after treatment, neither in eyes with severe NPDR groups nor eyes with PDR. Investigators found that IVB injection after panretinal photocoagulation gives insignificant difference in changes in central macular thickness with injection prior to laser treatment.