Tideman JWL, Pärssinen O, Haarman AEG, et al. - Experts aspired to explore whether a common set of genetic variants are correlated with susceptibility to high myopia (HM), low myopia (LM), and hyperopia. This genetic association study evaluated unrelated UK Biobank candidates 40 to 69 years of age of European and Asian ancestry. In total, 51,841 unrelated individuals of European ancestry and 2,165 unrelated individuals of Asian ancestry were assigned to a specific refractive error group and involved in the analyses. Genetic risk variants were found in HM, LM, and hyperopia samples, as well as in European and Asian samples. When compared to people with LM, people with HM inherited a greater number of variants from the same set of myopia-predisposing alleles and no different risk alleles. Such findings imply that treatment interventions aimed at common genetic risk variants linked to refractive error could be effective against both LM and HM.