Kalil CLPV, et al. - The variations in the skin related to the use of ortho-silicic acid stabilized by hydrolyzed collagen were comprehensively analyzed in this trial. a daily dose of 600 mg of ortho-silicic acid stabilized by hydrolyzed collagen exhibited positive results in skin rejuvenation based on the clinical assessment in firmness, hydration, and skin texture. In order to affirm the findings, advanced research was warranted.