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Ethnic differences in 90-day poststroke medication adherence

Stroke May 18, 2019

Lank RJ, et al. - As a first step in assessing the higher risk of stroke recurrence in Mexican Americans vs non-Hispanic whites, researchers evaluated ethnic differences in medication adherence 3 months after stroke occurrence in a population-based study. From 2008 to 2015, ischemic stroke cases from the Brain Attack Surveillance in Corpus Christi project in Texas were prospectively followed for 3 months after the stroke to evaluate adherence to medication, including statins, antiplatelets, anticoagulants, antihypertensives, and antidepressants. Mexican Americans were younger vs non-Hispanic whites, had more diabetes mellitus and hypertension, and less atrial fibrillation, smoking, and education. There was no significant difference in terms of sex, insurance status, high cholesterol, previous history of stroke / transient ischemic attack, excessive use of alcohol, tissue-type plasminogen activator treatment, National Institutes of Health Stroke Scale score, and ethnicity co-morbidity index between the two groups. No significant difference was found in medication adherence for any of the 5 drug classes between Mexican Americans and non-Hispanic whites, which challenges this issue as a reason for differences in stroke recurrence at the patient level. Provider and health system factors should be explored.

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