Khattab FM, et al. - In the present study, the researchers sought to evaluate serum levels of neutrophil activation marker (calprotectin) in patients with cutaneous lichen planus with different subtypes and made a comparison with healthy people. Peripheral blood samples from 30 lichen planus patients and 30 healthy people were compared. There was no correlation found between calprotectin serum levels and patients' ages, gender, disease duration, or the presence or strength of pruritus. However, there was a strong positive correlation between the presence of oral lesions and the number of locations. Calprotectin can be used to assess the severity and progression of lichen planus. Calprotectin has been linked to the pathogenesis of lichen planus.