Kitojo C, Gutman JR, Chacky F, et al. - Malaria test results from pregnant women screened at their first antenatal care visits at healthcare facilities (private and public) in all 184 districts of Tanzania between Jan 1, 2014, and Dec 31, 2017, were obtained from the Health Management Information Systems and District Health Information System 2 in order to contrast malaria test outcomes during antenatal care to two population-based prevalence surveys in Tanzanian children aged 6–59 months to investigate their potential in measuring malaria trends and progress towards elimination. To evaluate heterogeneity in transmission at finer resolution vs population-based surveys, routine antenatal care-based screening could be used, and it gave sample sizes powered to discover variations, significantly in areas of low transmission where surveys lack power. Decreases in predominance at antenatal care may lag behind those among children, reflecting the significance of monitoring burden and persisting prevention efforts among pregnant women as transmission reductions. The pregnancy-specific advantages and cost-efficiency of antenatal care-based screening continued to be evaluated.