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Estimated glomerular filtration rate and risk of poor outcomes after stroke

European Journal of Neurology Jul 23, 2019

Vart P, et al. - By analyzing data from the Norfolk and Norwich Stroke Registry from between January 2003 and April 2015, researchers explored the connection between estimated glomerular filtration rate (eGFR) and complications after stroke for the entire clinical spectrum of eGFR and for the fluctuation in eGFR during the hospital stay. The outcomes of interest were all-cause mortality, recurrent stroke, incident myocardial infarction, prolonged hospital stay and stroke disability at discharge. They followed 10,329 patients with stroke (mean age 77.8 years) for a mean of 2.9 years (30,126 person-years). Findings revealed that stroke patients with eGFR < 45 ml/min/1.73 m2 at hospital admission and >5% decrease or increase in eGFR during hospital stay were at a considerably greater danger of poor outcomes, especially all-cause mortality, myocardial infarction, prolonged hospital stay and disability at discharge.

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