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Estimated glomerular filtration rate and risk of poor outcomes after stroke

European Journal of Neurology Jun 30, 2019

Vart P, et al. - Since the connection between the estimated glomerular filtration rate (eGFR) and complications after stroke was not fully described for the entire eGFR clinical spectrum and the fluctuation of eGFR during the hospital stay, researchers by examining data from the Norfolk and Norwich Stroke Registry recorded between January 2003 and April 2015 sought to analyze eGFR and risk of poor outcomes after stroke. Investigators found that stroke patients with eGFR <45 mL/min/1.73m2 at hospital admission and > 5% decrease or rise in eGFR during hospital stay were at significantly high risk of poor results, especially all-cause mortality, myocardial infarction, prolonged hospital stay and disability at discharge. Except for recurrent stroke, the results were similar for other outcomes.
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