Farrell D, et al. - Via retrospectively analyzing 230 consecutive bone marrow biopsies, researchers studied the rate of detection of Epstein-Barr virus (EBV) expression in bone marrow samples and correlated any positive findings with various clinical parameters including patient's age, sex, clinical history, immune status, and any neoplastic transformation where follow-up data are available. By in situ hybridization, five cases (2.17%) with scattered EBV-positive cells were found. The EBV-positive cells that have been observed are largely small in size and are likely to represent bystander, latently infected cells. In immunodeficient people vs in immunocompetent patients, a slightly higher rate of detection of EBV-positive cells in the bone marrow was noted; 3% and 1%, respectively. In immunodeficient individuals (3%), the detection rate of EBV-positive cells in the bone marrow seems to be slightly higher vs in immunocompetent patients (1%).