Yu CW, et al. - In this 11-year study, researchers assessed trends of sepsis incidence and assessed mortality outcomes between sepsis patients admitted from emergency department (ED) vs non-ED routes using a nationwide health insurance database from Taiwan. From 2002 until 2012, a reduction in mortality from 27.2% to 21.1% was observed in ED-admitted sepsis patients and a reduction from 35.3% to 30.7% was reported in non-ED admitted sepsis patients. patients admitted through the ED vs those who were directly admitted had better outcomes in mortality, length of intensive care unit stay, and hospital stay, though a higher incidence of organ dysfunction was also observed among them. A 7% lower risk of 90-day mortality was observed in ED-admitted patients vs directly admitted patients, following propensity score matching.