Woll C, et al. - A cross-sectional study was conducted to help guide empiric treatment of infants ≤60 days old with suspected invasive bacterial infection by describing pathogens and their antimicrobial susceptibilities. Between July 1, 2011, and June 30, 2016, a cross-sectional study of infants ≤60 days old with invasive bacterial infection (bacteremia and/or bacterial meningitis) assessed in the Emergency Departments of 11 children's hospitals. Data reported that the combination of ampicillin plus either gentamicin or a third-generation cephalosporin was an appropriate empiric antimicrobial treatment regimen for most infants ≤60 days old evaluated in a Pediatric Emergency Department for suspected invasive bacterial infection. Findings revealed that 11% were resistant to third-generation cephalosporins alone of the pathogens isolated from infants with invasive bacterial infection.