Kiss Z, et al. - Experts conducted a meta-analysis to examine the available data regarding eosinophil density in healthy tissue specimen originating from lower gastrointestinal segments to support suggested diagnostic cutoffs widely used in clinical practice. A systematic search was performed in 3 different databases and calculations were made with Comprehensive MetaAnalysis software utilizing random-effects model. This investigation did not support the higher (>20) or lower (<10) cutoff values for healthy tissue eosinophil number. There was no normal cutoff eosinophil density in the small intestine and the colon in contrast to the esophagus.