Alkhalil M, et al. – In this study, researchers investigated the link between eosinopenia and infarct severity and how this relationship may determine long-term outcomes following ST-segment elevation myocardial infarction. The study sample consisted of 606 patients undergoing primary percutaneous coronary interventions from a high-volume single center. A total of 65% of the patients had eosinopenia. As measured by troponin value and left ventricular systolic function on echocardiography, patients in the low eosinophil group had bigger infarct sizes. A weak relationship between eosinophil count and both troponin and ejection fraction was observed. In patients with eosinopenia, the primary endpoint was greater. In 55.6% of patients, a discordance between eosinopenia and severe left ventricle systolic dysfunction was noted. In those with non-severe left ventricle dysfunction, eosinopenia was linked to worse clinical outcomes, but not in those with severe left ventricular dysfunction in comparison to those with the normal count. Hence, eosinopenia was concluded to be an easily ascertained marker that highlighted worse clinical outcomes over long-term follow-up.