Shorstein NH, Liu L, Carolan JA, et al. - In this retrospective clinical cohort study, researchers estimated the correlation of cefuroxime and moxifloxacin in relation to the occurrence of endophthalmitis following phacoemulsification cataract surgery. Patients with noncomplex phacoemulsification cataract surgery were studied in Kaiser Permanente Northern California during 2014-2019. Of 216,141 surgeries, endophthalmitis developed in 0.020% of moxifloxacin injected eyes and 0.013% of cefuroxime eyes. Endophthalmitis cases with positive cultures were usually associated with organism resistance in cefuroxime eyes but to sensitive organisms in moxifloxacin eyes. In eyes with a greater ACV, moxifloxacin doses may have been inadequate.