Li M, et al. - As removal of cells from the trophectoderm, the outer layer of the blastocyst, which subsequently forms the placenta, is commonly performed in preimplantation genetic testing, this testing may correlate with an increased risk for adverse outcomes linked with abnormal placentation. Researchers conducted a retrospective analysis of autologous frozen embryo transfer cycles that resulted in singleton live births per the Society for Assisted Reproductive Technology Clinical Outcomes Reporting System with the aim to compare the perinatal outcomes of singleton pregnancies conceived following frozen embryo transfer of a single, autologous blastocyst either with vs without preimplantation genetic testing. In this analysis, they included 16,246 frozen embryo transfers resulting in singleton births. Of these, 6,244 involved the transfer of a single blastocyst that had undergone preimplantation genetic testing, and the rest (n = 10,002) involved the transfer of a single blastocyst that had not undergone a biopsy. Overall findings suggest a small increase in the likelihood of preterm birth in correlation with the frozen embryo transfer cycles with preimplantation genetic testing vs those without preimplantation genetic testing. Although there appeared a modest increase in the risk for prematurity, further investigation is required.