Rabban JT, Devine P, Sangoi AR, et al. - In order to develop the morphological spectrum of this tumor, researchers present three additional cases that exhibited adenosarcoma-like features not previously reported, one of which is the first reported to respond to targeted therapy. They further assessed 19 conventional uterine adenosarcomas for evidence of NTRK rearrangement. They started deep cervical wall invasion in two cases at hysterectomy while the polypectomy removed the third case. It was noted that none of the uterine adenosarcomas indicated any S100 or pan-Trk staining or rearrangement of NTRK1, NTRK2 or NTRK3 by next-generation sequencing. The results displayed that unusual adenosarcoma-like spindle cell neoplasms of the cervix may represent an NTRK fusion sarcoma, which can be identified by S100 and pan-Trk staining and validated by NTRK molecular testing. In addition, they noted that conventional uterine adenosarcomas do not harbor NTRK rearrangements.