Bjornstad P, et al. - Given that elevated serum uric acid (SUA) in adults with diabetes is becoming more recognized as a risk factor for kidney disease, researchers assessed if elevated SUA can forecast future development of elevated urinary albumin excretion (UAE) and hypertension (defined as systolic or diastolic blood pressure ≥130/80 mmHg) in teens with type 2 diabetes (T2D). In the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) study, 539 obese youth (aged 12-17 years) with T2D duration < 2 years at baseline, serum creatinine, cystatin C, SUA, and urine albumin-to-creatinine ratio (UACR) were evaluated. In T2D youth, findings revealed that hyperuricemia is common. The risk of hypertension onset and elevated UAE were independently increased by higher baseline SUA. Research is needed to determine if development of diabetic kidney disease and hypertension in young people with T2D can be impeded by SUA-lowering therapies.