Özkan G, et al. - In this study including 131 chronic kidney disease (CKD) patients and 34 healthy controls, researchers focused on the link between procollagen C-proteinase enhancer-1 (PCPE-1) and CKD. They determined PCPE-1 levels in CKD and recorded demographic data and performed routine biochemical tests. They compared the control and patient groups in terms of demographic data, biochemical test results and PCPE-1 levels. Parameters affecting PCPE-1 levels in the patient group were assessed. Findings revealed high PCPE-1 levels in CKD patients, inferring that PCPE-1 could be related to disease progression in these patients, as suggested by PCPE-1 levels being negatively correlated with GFR.